The Progress of Experiment: Science and Therapeutic Reform in the United States, 1900-1990 (Cambridge Studies in the History of Medicine) Shopping

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Product Name : The Progress of Experiment: Science and Therapeutic Reform in the United States, 1900-1990 (Cambridge Studies in the History of Medicine)

This book explores the origins of our contemporary system of drug regulation and the modern clinical trial. Marks illustrates the symbiotic relationship between the history of modern drug regulation and the history of therapeutic reform. Accompanying this history of public policy is a detailed account of changing experimental ideals and practices. Marks traces the history of therapeutic experimentation, from the "collective investigations" of the past century to the controlled clinical trial that emerged after 1950 as the paradigm of scientific experimentation. The result is the first general history of clinical research in the United States, a book that examines therapeutic experiments in a wide range of diseases, from syphilis and pneumonia to heart disease and diabetes.

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Product Description : The Progress of Experiment: Science and Therapeutic Reform in the United States, 1900-1990 (Cambridge Studies in the History of Medicine)

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Making Mice: Standardizing Animals for American Biomedical Research, 1900-1955 Shopping

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Making Mice blends scientific biography, institutional history, and cultural history to show how genetically standardized mice came to play a central role in contemporary American biomedical research.

Karen Rader introduces us to mouse "fanciers" who bred mice for different characteristics, to scientific entrepreneurs like geneticist C. C. Little, and to the emerging structures of modern biomedical research centered around the National Institutes of Health. Throughout Making Mice, Rader explains how the story of mouse research illuminates our understanding of key issues in the history of science such as the role of model organisms in furthering scientific thought. Ultimately, genetically standardized mice became icons of standardization in biomedicine by successfully negotiating the tension between the natural and the man-made in experimental practice.

This book will become a landmark work for its understanding of the cultural and institutional origins of modern biomedical research. It will appeal not only to historians of science but also to biologists and medical researchers.

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