Buy The Xeno Chronicles: Two Years on the Frontier of Medicine Inside Harvard's Transplant Research Lab

The Xeno Chronicles: Two Years on the Frontier of Medicine Inside Harvard's Transplant Research Lab by BBS / PublicAffairs [2005], New York

Dr. David H. Sachs of the Harvard Medical School and Massachusetts General Hospital is not a household name, but within medical science, he is a giant. An immunologist and surgeon, Sachs has made significant contributions in the field of organ transplantation. But Sachs's real passion— and the possibility for a revolution in medicine—lays in xenotransplantation: using animal parts to treat sick people. "Xeno" might save the lives of untold thousands. It could also lead to a multi-billion-dollar business.

Millions of dollars have been invested in Sachs's work in the hopes of staking a lucrative claim in the future of medicine. As The Xeno Chronicles begins, Sachs's decades of work and hopes have all converged on a genetically engineered, cloned pig named Goldie, whose organs have been designed not to be rejected by their recipients. Experiments begin but just as Sachs begins to get unprecedented results, he loses his biggest financial support and the collaboration of an important outside lab. He is almost sixty-two. Time and money are starting to run out.

G. Wayne Miller's absorbing, dramatic narrative account of a brilliant scientist's attempts to achieve a breakthrough offers an illuminating look into the minds, hearts, labs, and practical realities of those on the very forefront of medical science. Based on exclusive and unprecedented inside-the-lab access, The Xeno Chronicles clarifies both how science works and the ethical issues it raises through an absorbing human story and intimate portrait of Sachs, his colleagues, and patients.

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Now revised and updated, this acclaimed book takes an in-depth look at the latest scientific research in to the brain. Pulitzer Prize-winner Ronald Kotulak reveals n ew understandings of how nature builds the brain then develo ps it during early life. '

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Inside the Mayo Clinic is John Shepherd’s fascinating tale of an Irish academic who tested the rules in boarding school, stood watch as a medical student against German bombers in Belfast, and, inspired by The Doctors Mayo, set sail for the United States to work at the famed clinic as a Fulbright scholar on sabbatical from Queen’s University. Three years later, Shepherd moved his family to Rochester, Minnesota, to begin his career as a researcher at the renowned medical practice.

Nearly half a century later, this son and grandson of Presbyterian ministers weaves generous doses of Celtic humor into his historical account of Mayo’s evolution from simple frontier practice to cutting-edge clinic. From his perspective—as researcher, medical school dean, and esteemed member of the clinic’s boards of governors, trustees, and development—Shepherd relates unique insights about explosive growth at Mayo during the past five decades. Recounting the dramatic changes he has not only witnessed firsthand but also helped bring about, he remarks on the colorful cast of colleagues and characters—from royalty to presidents to corporate moguls—with whom he met and worked at what is, arguably, the world’s best-known medical institution.

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