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Product Name : Statistical Issues in Drug Development

Statistics in Practice A new series of practical books outlining the use of statistical techniques in a wide range of application areas:
* Human and Biological Sciences
* Earth and Environmental Sciences
* Industry, Commerce and Finance
Statistical Issues in Drug Development Stephen Senn Professor of Pharmaceutical & Health Statistics, University College, London Statistical Issues in Drug Development provides an accessible text for those working directly in drug development, regulatory and marketing departments within the pharmaceutical industry. As a consequence of regulatory authorities demanding increasingly higher standards, statistics has become a critical element in the design and conduct of drug development programmes. The concepts covered in this volume guide the non-statistician through the most pressing statistical issues and controversies in drug development. Key issues covered include:
* Design & interpretation of clinical trials
* Bayesian & frequentist methods
* Sequential & cross-over trials
* Drug monitoring & pharmaco-economics
The book has been prepared in two sections. The first section considers the role of statistics in drug development from four different perspectives: historical, philosophical, technical and professional. The second section covers a series of controversial topics such as fixed versus random effects for meta-analysis, one-sided versus two-sided tests and the ethics of placebo run-ins. The approachable and wide-ranging coverage of this book will make it invaluable to all those working in drug development and regulation.

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Important new textbook gives students of pharmacy a one-stop resource to develop the necessary skills to find, read, understand, and evaluate drug literature. Epidemiological and mathematical concepts are explained clearly and concisely with real examples, not hypothetical case studies. Key concepts correlation and regression analysis, survival curve analysis, medical informatics, research process and experimental design are presented clearly and made relevant to the pharmacy arena.

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Quick Look Electronic Drug Reference 2006 contains all the features of Quick Look Drug Book 2006 including thousands of trade and generic drug names in an easy-to-use electronic format—plus audio pronunciations, keyword/therapeutic category index, quick cross-referencing, and full-color images of the top 200 prescribed drugs. Versatile search functions allow searching the index, searching the full content, searching within a previous search, or searching on part of a word (ex: *mide finds all drug names ending with "mide"). Four-way viewing lists information by generic and trade name, generic only, "sound-alike" drugs, or user-added topics. Add-a-topic lets you add drug names to the A-to-Z index. Add-a-note lets you annotate an existing drug topic. Bookmarks allow you to create a list of frequently referenced drug topics.
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Drug discovery increasingly requires a common understanding by researchers of the many and diverse factors that go into the making of new medicines. The scientist entering the field will immediately face important issues for which his education may not have prepared him: project teams, patent law, consultants, target product profiles, industry trends, Gantt charts, target validation, pharmacokinetics, proteomics, phenotype assays, biomarkers, and many other unfamiliar topics for which a basic understanding must somehow be obtained. Even the more experienced scientist can find it frustratingly difficult to get an overview of the many factors involved in modern drug discovery and often only after years of exploring does a whole and integrated picture emerge in the mind of the researcher.
Real World Drug Discovery: A Chemist’s Guide to Biotech and Pharmaceutical Research presents this kind of map of the landscape of drug discovery. In a single, readable volume it outlines processes and explains essential concepts and terms for the recent science graduate wondering what to expect in pharma or biotech, the medicinal chemist seeking a broader and more timely understanding of the industry, or the contractor or collaborator whose understanding of the commercial drug discovery process could increase the value of his contribution to it.

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- "Periodic Table of Drugs" listing current top-selling drugs arranged by target and laid out so that structural similarities and differences are plain and clear, with regular updates available at the book's website.
- Extensive use of diagrams to illustrate concepts like biotech startup models, preteomic profiling for target identification, Gantt charts for project planning, etc.

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