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Apply adaptive research to improve results in drug development
The pharmaceutical industry today faces a deepening crisis: inefficiency in its core business, the development of new drugs. The Agile Approach to Adaptive Research offers a solution. It outlines how adaptive research, using already-available tools and techniques, can enable the industry to streamline clinical trials and reach decision points faster and more efficiently.
With a wealth of real-world cases and examples, author Michael Rosenberg gives readers a practical overview of drug development, the problems inherent in current practices, and the advantages of adaptive research technology and methods. He explains the concepts, principles, and specific techniques of adaptive research, and demonstrates why it is an essential evolutionary step toward improving drug research and development.
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The adaptive concept
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Agile clinical development
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Statistics in adaptive research, including frequentist and Bayesian approaches
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Statistics in Practice A new series of practical books outlining the use of statistical techniques in a wide range of application areas: * Human and Biological Sciences * Earth and Environmental Sciences * Industry, Commerce and Finance Statistical Issues in Drug Development Stephen Senn Professor of Pharmaceutical & Health Statistics, University College, London Statistical Issues in Drug Development provides an accessible text for those working directly in drug development, regulatory and marketing departments within the pharmaceutical industry. As a consequence of regulatory authorities demanding increasingly higher standards, statistics has become a critical element in the design and conduct of drug development programmes. The concepts covered in this volume guide the non-statistician through the most pressing statistical issues and controversies in drug development. Key issues covered include: * Design & interpretation of clinical trials * Bayesian & frequentist methods * Sequential & cross-over trials * Drug monitoring & pharmaco-economics The book has been prepared in two sections. The first section considers the role of statistics in drug development from four different perspectives: historical, philosophical, technical and professional. The second section covers a series of controversial topics such as fixed versus random effects for meta-analysis, one-sided versus two-sided tests and the ethics of placebo run-ins. The approachable and wide-ranging coverage of this book will make it invaluable to all those working in drug development and regulation.
Product Description : Statistical Issues in Drug Development
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The continuing professional development (CPD) of physicians, formerly called continuing medical education, greatly expands what physicians can do with the help of educational experts to provide optimal patient care. This book brings together more than two dozen noted contributors from throughout the medical education field to consider how the evolution of the physician workforce is affecting the approach to lifelong learning. All who are dedicated to assisting physicians in that learning and improving health care will find the book to be forward-looking, comprehensive, thought-provoking and informative.
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Product Name : Fast Facts for Curriculum Development in Nursing: How to Develop & Evaluate Educational Programs in a Nutshell
This new addition to the Fast Facts series is a pithy guide for novice nurse educators to the development, revision, and evaluation of programs and curricula that meet the standard requirements of the National Council of State Boards of Nursing, the NLNAC, and CCNE.
Applying the concepts and principles of Systems Theory, the guide moves through the development process to include evaluation procedures where decisions are based on data. It addresses the common definitions of curriculum, how to design a curriculum, and how to design courses in accordance with the organizing elements of the program. The guide covers the purposes and development of a mission statement and of a program philosophy, as well as how to select an organizational framework. Curriculum implementation and faculty development requirements are also explored, in addition to educational and program outcomes and their evaluation. Organized for quick access and ease of use, each chapter defines key terms, summarizes important points, and lists resources for additional study.
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Product Description : Fast Facts for Curriculum Development in Nursing: How to Develop & Evaluate Educational Programs in a Nutshell
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Clinicians and those in health sciences are frequently called upon to measure subjective states such as attitudes, feelings, quality of life, educational achievement and aptitude, and learning style in their patients. This fourth edition of Health Measurement Scales enables these groups who often have limited knowledge of statistics, to both develop scales to measure non-tangible health outcomes, and better evaluate and differentiate between existing tools.
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Making Sense of Factor Analysis: The Use of Factor Analysis for Instrument Development in Health Care Research presents a straightforward explanation of the complex statistical procedures involved in factor analysis. Authors Marjorie A. Pett, Nancy M. Lackey, and John J. Sullivan provide a step-by-step approach to analyzing data using statistical computer packages like SPSS and SAS. Emphasizing the interrelationship between factor analysis and test construction, the authors examine numerous practical and theoretical decisions that must be made to efficiently run and accurately interpret the outcomes of these sophisticated computer programs.
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