Best How Science Works: Evaluating Evidence in Biology and Medicine

How Science Works: Evaluating Evidence in Biology and Medicine by Oxford University Press, USA




One week, red wine is good for the heart. The next week, new reports say it's bad for the health. So which is true? Anyone who's ever read science news with fascination, or who's ever been confounded by conflicting stories will appreciate this book. Taking a look at some true to life contemporary news stories, the author assesses recent studies on topics ranging from vitamin C and caffeine to pollution and cancer. With straight talk and a passion for the whole project of science, he demysifies the cult of the expert and sheds light on the nitty-gritty details of scientific processes. Any scientist loves a challenge, but the biggest challenge of all, observes Jenkins, is shared by scientists and nonscientitsts alike: how to make practical decisions in light of ambiguous evidence. Promising no simple answers, this book does offer excellent food for thought for people pondering that next glass of wine.Read more How Science Works: Evaluating Evidence in Biology and Medicine

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Just A Theory: Exploring The Nature Of Science

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The Fourth Edition of Evaluating Research in Communicative Disorders explains and discusses how to read, understand, and evaluate research published in communicative disorders and sciences journals. This text is broken down into three parts. Part I introduces the basic principles for evaluating research, Part II contains a excerpts from journal articles and Part III presents two complete articles for student evaluation accompanied by an evaluation checklist to guide the student in the evaluation process. Numerous examples from current research to illustrate and clarify points made in the text. The book is richly illustrated with tables and figures and includes many study questions to guide students through primary sources in the research literature.

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The Gravity of JUPITER (Justification for the Use of Statins in Primary Prevention: An Intervention Trial Evaluating Rosuvastatin) (Postgraduate Medicine) Description

In the recently published Justification for the Use of Statins in Primary Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) study, a large randomized, placebo-controlled trial, rosuvastatin proved to be safe and remarkably effective in the setting of primary prevention. In patients without coronary heart disease or diabetes, with a baseline low-density lipoprotein cholesterol (LDL-C) level < 130 mg/dL and a C-reactive protein (CRP) ≥ 2 mg/L, a statin-induced LDL-C reduction of 50% reduced serious cardiac events by about 50%, including in women and the elderly, and also lowered all-cause mortality. The mean on-treatment LDL-C level (55 mg/dL) in the rosuvastatin arm of JUPITER was about in the mid-range of the physiologically normal levels. C-reactive protein screening should be considered, especially in patients without preexisting indications for statin therapy. In general, the CRP-lowering efficacy of statin therapy is directly and significantly correlated with its LDL-C–lowering activity. Simvastatin, at the 80-mg daily dose, is more toxic to muscles and liver than other statins at their highest dose, and thus should be used with caution.

Original Publication Date: May 2009