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This book will explore the great opportunities and challenges which exist in conducting clinical trials in developing countries. By exploring the various regulations specific to the major players and providing insight into the logistical challenges including language barriers, this book provides a working tool for clinical researchers and administrators to navigate the intricacies of clinical trials in developing countries. Important topics such as ethical issues will be handled very carefully to highlight the significant differences of conducting this work in various jurisdictions. Overall, it will present a clear and comprehensive guide to the ins-and-outs of clinical trials in various countries to assist in design, development, and effectiveness of these trials.

• Contributors include high-profile, respected figures who have paved the way for clinical trials in developing countries

• Provides hands-on tools for regulatory and legal requirements and qualification, design, management, and reporting

• Case studies outline successes, failures, lessons learned and prospects for future collaboration

• Includes country-specific guidelines for the most utilized countries

• Foreword by David Feigel, former Head of CDRH at FDA

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The phenomenal growth of global pharmaceutical sales and the quest for innovation are driving an unprecedented search for human test subjects, particularly in middle- and low-income countries. Our hope for medical progress increasingly depends on the willingness of the world's poor to participate in clinical drug trials. While these experiments often provide those in need with vital and previously unattainable medical resources, the outsourcing and offshoring of trials also create new problems. In this groundbreaking book, anthropologist Adriana Petryna takes us deep into the clinical trials industry as it brings together players separated by vast economic and cultural differences. Moving between corporate and scientific offices in the United States and research and public health sites in Poland and Brazil, When Experiments Travel documents the complex ways that commercial medical science, with all its benefits and risks, is being integrated into local health systems and emerging drug markets.

Providing a unique perspective on globalized clinical trials, When Experiments Travel raises central questions: Are such trials exploitative or are they social goods? How are experiments controlled and how is drug safety ensured? And do these experiments help or harm public health in the countries where they are conducted? Empirically rich and theoretically innovative, the book shows that neither the language of coercion nor that of rational choice fully captures the range of situations and value systems at work in medical experiments today. When Experiments Travel challenges conventional understandings of the ethics and politics of transnational science and changes the way we think about global medicine and the new infrastructures of our lives.

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This book provides a comprehensive epidemiological perspective on cardiovascular diseases and analysis of measures for their prevention and control in community and clinical settings. Perfect for both students and practitioners, the second edition includes over 300 tables, figures, and exhibits; and has been thoroughly updated to reflect the most recent research in the field.

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Awakening Hippocrates: A Primer on Health, Poverty, and Global Service takes aim on helping health professionals better understand the reasons for global health disparities. The primer outlines the reasons why health professionals are essential to affecting change in current global affairs and how they can participate in serving those who are in need. Beginning with an in-depth examination of the state of global health, the author draws on his personal experience to illustrate the enormous impact that health professionals can have in changing the future of health care. Awakening Hippocrates also profiles seven exemplary health professionals who have dedicated their lives to service and are a source of inspiration to those interested in medical volunteering.Read more Awakening Hippocrates: A Primer on Health, Poverty, And Global Service

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Collaboration between The Lancet and Imperial College London, UK, has resulted in a new Commission, which examines how medical technology should best be used to improve health in low- and middle-income countries. The report concludes that in many cases, medical technology—almost exclusively developed in rich countries—is simply inappropriate for use in poorer nations.

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