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For the last 150 years, industrial, agricultural and household chemicals have been tested on animals for the alleged purpose of protecting the public from their dangerous effects. Through a meticulous analysis of the technical and scientific problems that have plagued animal tests for decades, this book reveals that using animals as human surrogates is not only unethical, it is bad science.

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Designing and Conducting Research in Health and Human Performance shows students how to become effective producers and consumers of health and human performance research. The book provides comprehensive coverage of both quantitative and qualitative research methods and includes step-by-step guidance for writing effective research proposals and theses. In addition, the authors show how to read, assess, interpret, and apply published research and how to conduct basic studies in health, physical education, exercise science, athletic training, and recreation.

Designing and Conducting Research in Health and Human Performance is filled with illustrative examples that emphasize the real-world applications of research methods. Throughout, the authors draw on a variety of examples that were selected because they provide a context to further the understanding of health and human performance research.

Research to Practice examples and Tips are included by the authors to help students better appreciate the book's content. These study aids provide suggestions and additional resources to assist students in understanding the research process. Key Terms, defined and highlighted, enrich each chapter. Chapter Review Questions, designed to help students comprehend and follow best practices in research methods, close each chapter. Online resources and guides developed by the authors to support and enhance students' learning of important research concepts are available.

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The Growth of the Surface Area of the Human Body by Univ Of Minnesota Press




Dr. Boyd has reviewed in her monograph all the literature on the measurement and estimation of the surface area of the human body and has tabulated the data on 1,114 subjects. Most of her calculations are based on 231 subjects for whom the data were reasonably complete. She has analyzed statistically the various methods of measurement and 36 formulae for the estimation of body surface. The surface area of the body of human subjects and experimental animals has assumed greater prominence during the last two decades and at present is employed by many physiologists as a basis of reference for estimating basal metabolism, vital capacity, cardiac output, etc. Dr. Boyd is particularly interested in the anatomical relationship to growth and has included in her studies the prenatal as well as the postnatal period. This small monograph is carefully written, and it contains many valuable tables and figures. It will doubtless remain the standard work of reference for many years.Read more The Growth of the Surface Area of the Human Body

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The phenomenal growth of global pharmaceutical sales and the quest for innovation are driving an unprecedented search for human test subjects, particularly in middle- and low-income countries. Our hope for medical progress increasingly depends on the willingness of the world's poor to participate in clinical drug trials. While these experiments often provide those in need with vital and previously unattainable medical resources, the outsourcing and offshoring of trials also create new problems. In this groundbreaking book, anthropologist Adriana Petryna takes us deep into the clinical trials industry as it brings together players separated by vast economic and cultural differences. Moving between corporate and scientific offices in the United States and research and public health sites in Poland and Brazil, When Experiments Travel documents the complex ways that commercial medical science, with all its benefits and risks, is being integrated into local health systems and emerging drug markets.

Providing a unique perspective on globalized clinical trials, When Experiments Travel raises central questions: Are such trials exploitative or are they social goods? How are experiments controlled and how is drug safety ensured? And do these experiments help or harm public health in the countries where they are conducted? Empirically rich and theoretically innovative, the book shows that neither the language of coercion nor that of rational choice fully captures the range of situations and value systems at work in medical experiments today. When Experiments Travel challenges conventional understandings of the ethics and politics of transnational science and changes the way we think about global medicine and the new infrastructures of our lives.

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This pioneering book explores the landscape of human consciousness induced by LSD and other psychedelics. Author Stanislav Grof shows the relationship between shamanism, near-death experiences, and other mystical and altered states with those induced by psychedelics.

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The Professional Guinea Pig documents the emergence of the professional research subject in Phase I clinical trials testing the safety of drugs in development. Until the mid-1970s Phase I trials were conducted on prisoners. After that practice was outlawed, the pharmaceutical industry needed a replacement population and began to aggressively recruit healthy, paid subjects, some of whom came to depend on the income, earning their living by continuously taking part in these trials. Drawing on ethnographic research among self-identified “professional guinea pigs" in Philadelphia, Roberto Abadie examines their experiences and views on the conduct of the trials and the risks they assume by participating. Some of the research subjects he met had taken part in more than eighty Phase I trials. While the professional guinea pigs tended to believe that most clinical trials pose only a moderate health risk, Abadie contends that the hazards presented by continuous participation, such as exposure to potentially dangerous drug interactions, are discounted or ignored by research subjects in need of money. The risks to professional guinea pigs are also disregarded by the pharmaceutical industry, which has become dependent on the routine participation of experienced research subjects. Arguing that financial incentives compromise the ethical imperative for informed consent to be freely given by clinical-trials subjects, Abadie confirms the need to reform policies regulating the participation of paid subjects in Phase I clinical trials.

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This book explores physical and behavioral characteristics that can be considered universal among all cultures, all people. It presents cases demonstrating universals, looks at the history of the study of universals, and presents an interesting study of a hypothetical tribe, The Universal People.

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This fully updated and revised edition of a classic guide to grant writing for health and human service professionals reflects the two major changes in the field: new NIH application processes and an increased emphasis on interprofessional and team approaches to science. New case examples reflect grant writing strategies for a great variety of health and human service professions, and the text includes an enhanced focus on online methods for organizing grant submissions. A new section on special considerations for submitting grants addresses specific types of research including community-based participatory research, mixed methods, behavioral intervention research, and dissertation and , mentorship proposals. The new chapter on common writing challenges and solutions provides examples of strong and weak statements and highlights the importance of writing with precision. Additionally, this new edition provides an expanded section on post-award requirements and links to NIH videos about grant writing.

Written for individuals in both academic and practice settings, the guide addresses, step-by-step, the fundamental principles for effectively securing funding. It is the only book to provide grant-writing information that encompasses many disciplines and to focus on building a research career with grant writing as a step-by-step process. It provides detailed, time-tested strategies for building an investigative team, highlights the challenges of collaboration, and describes how to determine the expertise needed for a team and the roles of co-investigators. The book addresses the needs of both novice and more experienced researchers.

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The Sacrifice provides a uniquely detailed account of the sociological context of animal experimentation. The authors provide a rich analysis of complex and changing role of the laboratory animal in the political and scientific culture of the United States and the United Kingdom. By understanding the interplay of the groups, the authors view the experimental controversy as an ongoing and constantly recreated set of social processes, not just a problem of morality.

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This book provides in-depth insights into the pathogenesis of human tuberculosis and can serve as both a guide for future research and for the treatment of the disease. It covers the seminal work of Max B. Lurie in the rabbit model of tuberculosis, and the work of the author, who continued to research using the rabbit model after Lurie's death in 1966. updates Lurie's last work that was published in 1964 covering tuberculosis in the rabbit model offers an authoritative account of the current research using the rabbit model presents the pathogenesis of tuberculosis from the inhalation of the bacillus to a fully developed disease and its various manifestations details the key principles of tuberculosis pathogenesis illustrations the pathology of human disease using images from the renowned collection of A. R. Rich and W. G. MacCallum of the Johns Hopkins School of Medicine provides a comparison of tuberculosis in rabbits, mice, guinea pigs, and monkeys.

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This is the first book to introduce and explain the sophisticated statistical methods used in human genetics research. It assumes an understanding of elementary statistical concepts and discusses the objectives, principles and limitations of these methods in detail.

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Cancer has long been cured in mice but not in people. Why? Successful laboratory treatments and cures for one species don't necessarily result in cures for humans. But, because practice has become economically entrenched within medical industry, animal experimentation -against all medical evidence- continues.The human benefits of animal experimentation- a bedrock of the scientific age- is a myth perpetuated by an amorphous but insidious network of multibillion-dollar special interests: research facilities, drug companies, universities, scientisits, and even cage manufacturers.C.Ray Greek, MD, and veterniary dermatologist, Jean Swingle Gree, DMV, show how the public has been deliberately misled and blow the lid off the vested-interest groups whose hidden agendas put human health at risk.

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With this valuable practical guide, three members of the Harvard Stem Cell Institute have compiled and edited the definite handbook for the exciting new field of human embryonic stem cell research. The editors have gathered protocols from scientists with extensive reputation and expertise, describing and comparing currently used techniques for the culture of human stem cells and discussing the strengths and weaknesses of the different approaches.

Human Embryonic Stem Cells: The Practical Handbook contains the first centralised collection of methods used in human embryonic stem cell biology. The book covers the derivation of human stem cell lines, the obtaining of cells from human stem cell banks, the culturing and characterisation of the cells, and the differentiation of the cells in vitro and in vivo. Lastly, almost all of these protocols can also be used for analyzing and manipulating induced pluripotency iPS stem cells. This allows an even greater number of opportunities for those interested in purusing work in pluripotent stem cells, disease modelling, and other aspects of basic regenerative medicine research.

The novel and useful focus of this book sets it apart from other available books:

• Compares and evaluates the protocols used in leading laboratories working on human embryonic stem cells
• Centred solely on practical protocols for human (not mouse) embryonic stem cell research
• Includes extensive troubleshooting sections
• Addresses the different proclivities and behaviours of individual human embryonic cell lines
• Contains techniques currently known only to a small number of specialised laboratories worldwide

This handbook represents an essential source of up-to-date practical information for all cell and developmental biologists working with human embryonic stem cells or wishing to enter the field. It is also essential reading for clinical researchers in areas such as diabetes, cardiovascular disease, and neurological diseases.

Praise from the reviews:

"...a highly readable and useful book… A notable feature of the book is its air of openness and honesty… This book… will help many to navigate the uncharted waters of human embryonic stem cell biology." BRITISH SOCIETY FOR CELL BIOLOGY

"... the imaginative solutions in this book can inspire us to get past our most frustrating limitations." CELL STEM CELL

"... the richness in the details of each protocol presented will certainly encourage more scientists to begin studies of Human pluripotent stem cells..."  REGENERATIVE MEDICINE

"In this fast-moving field, this [handbook] will help drive advances of more and more researchers."  DIFFERENTIATION

"...a valuable resource for seasoned and novice researchers... an excellent addition to the reference collection of any medical library or research laboratory." THE AMERICAN MEDICAL ASSOCIATION

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This easy-to-read reference book provides a practical approach for dealing with the legal and regulatory compliance issues involved in human research. Covering a broad range of topics, such as consent, confidentiality, subject recruitment and selection, the role of the investigator and Institutional Review Board, it offers timely and useful strategies for achieving regulatory compliance while reducing liability. In addition, insurance, quality management, accreditation, and risk management are topics examined in the book. The practical insights found in this volume are not found in other books on the subject. Clinical Trials and Human Research is a practical tool to help anyone involved in clinical research.

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"One of the funniest and most unusual books of the year....Gross, educational, and unexpectedly sidesplitting."—Entertainment Weekly

Stiff is an oddly compelling, often hilarious exploration of the strange lives of our bodies postmortem. For two thousand years, cadavers—some willingly, some unwittingly—have been involved in science's boldest strides and weirdest undertakings. They've tested France's first guillotines, ridden the NASA Space Shuttle, been crucified in a Parisian laboratory to test the authenticity of the Shroud of Turin, and helped solve the mystery of TWA Flight 800. For every new surgical procedure, from heart transplants to gender reassignment surgery, cadavers have been there alongside surgeons, making history in their quiet way.

In this fascinating, ennobling account, Mary Roach visits the good deeds of cadavers over the centuries—from the anatomy labs and human-sourced pharmacies of medieval and nineteenth-century Europe to a human decay research facility in Tennessee, to a plastic surgery practice lab, to a Scandinavian funeral directors' conference on human composting. In her droll, inimitable voice, Roach tells the engrossing story of our bodies when we are no longer with them.

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