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Over the past two decades there has been a great deal of international, specialized research activity focused on risk factors and prevention strategies for falls in older people. This book provides health care workers with a detailed analysis of the most recent developments in the area and helps bridge the gap between scientific journal articles and general texts. The volume is constructed in three parts: risk factors, prevention strategies, and future research directions. It includes coverage of the epidemiology, critical appraisal of the roles of exercise, environment, footwear, medication, evidence-based risk assessment, and targeted and individually tailored falls-prevention strategies. Falls in Older People will be invaluable to medical practitioners, physiotherapists, occupational therapists, nurses, researchers, and all those working in community, hospital and residential aged care settings.

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This book provides a comprehensive epidemiological perspective on cardiovascular diseases and analysis of measures for their prevention and control in community and clinical settings. Perfect for both students and practitioners, the second edition includes over 300 tables, figures, and exhibits; and has been thoroughly updated to reflect the most recent research in the field.

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This volume provides an overview of the important health promotion and disease prevention theories, methods, and policy issues. Applications of these theories and methods are reviewed to promote health through a variety of channels, for a variety of disease outcomes, and among a variety of populations. It can be used as a text for introductory causes to the field of health promotion and disease prevention, as well as a reference for researchers and practitioner's actively working in this area.

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Iatrogenic hypoglycemia, or low blood sugar caused by medical treatment, is a challenge facing people with diabetes and their health-care providers. Philip E. Cryer, MD, examines this persistent problem from a pathophysiological perspective.

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The last few years have seen enormous progress in terms of our understanding of the etiology and pathogenesis of cervical cancer (particularly with respect to the role of human papillomaviruses), and this has opened up new avenues for prevention. Additionally, there have been further refinements of existing technologies for cervical cancer control. To read about the state of the art on cervical cancer, health professionals have to locate individual articles and reviews of specific topics. In recognition of this, we propose to produce a book that will bring together in one place reviews of the contribution of descriptive and analytical epidemiological research to our understanding of cervical cancer etiology, as well as research on the application of that knowledge (plus knowledge gained from basic science investigations) to prevention through screening, chemoprevention, and vaccine development. The proposed book will include authoritative reviews by scientists working on the disciplines that are pertinent to the topic of the epidemiology and prevention of cervical cancer.

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Given with clear, systematic direction, the methods discussed in this book are an important first step in providing a rigorous, standardized approach to assessing the effectiveness and economic impact of public health prevention interventions. Developed from a course given at the Centers for Disease Control and Prevention, the Guide was reviewed by a panel of nationally-recognized experts in public health, decision analysis and economic analysis. It gives how-to explanations of study design, decision analysis, measures of effectiveness, and measures of cost, including cost-benefit analysis, cost-effectiveness analysis, and cost-utility analysis. Appendices contain a variety of useful material including an account of illustrative case studies in decision analysis and economic analysis, numerous data tables and indices, and a discussion of attribution. In addition to providing systematic methodology, the book makes specific recommendations on standardizing methods for discount rates, study perspective, willingness-to-pay measures, analytic horizon and more.
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In the recently published Justification for the Use of Statins in Primary Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) study, a large randomized, placebo-controlled trial, rosuvastatin proved to be safe and remarkably effective in the setting of primary prevention. In patients without coronary heart disease or diabetes, with a baseline low-density lipoprotein cholesterol (LDL-C) level < 130 mg/dL and a C-reactive protein (CRP) ≥ 2 mg/L, a statin-induced LDL-C reduction of 50% reduced serious cardiac events by about 50%, including in women and the elderly, and also lowered all-cause mortality. The mean on-treatment LDL-C level (55 mg/dL) in the rosuvastatin arm of JUPITER was about in the mid-range of the physiologically normal levels. C-reactive protein screening should be considered, especially in patients without preexisting indications for statin therapy. In general, the CRP-lowering efficacy of statin therapy is directly and significantly correlated with its LDL-C–lowering activity. Simvastatin, at the 80-mg daily dose, is more toxic to muscles and liver than other statins at their highest dose, and thus should be used with caution.

Original Publication Date: May 2009