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Successfully tested in the authors' courses at Boston University and Harvard University, this text combines theory and practice in presenting traditional and new epidemiologic concepts. Broad in scope, the text opens with five chapters covering the basic epidemiologic concepts and data sources. A major emphasis is placed on study design, with separate chapters devoted to each of the three main analytic designs: experimental, cohort, and case-control studies. Full chapters on bias, confounding, and random error, including the role of statistics in epidemiology, ensure that students are well-equipped with the necessary information to interpret the results of epidemiologic studies. An entire chapter is also devoted to the concept of effect measure modification, an often-neglected topic in introductory textbooks. Up-to-date examples from the epidemiologic literature on diseases of public health importance are provided throughout the book. The second edition has been thoroughly revised with up-to-date examples and data from epidemiologic literature and features over 100 new study questions.

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Mastering the art of communicating scientific information is more critical than ever for a successful career in science and technology. Scientists today must be able to effectively convey sophisticated information to a broad audience that may include students, colleagues around the world, regulatory bodies, granting agencies, legislators, and the lay public. In this engaging and lively book, the author provides a step-by-step guide to the complete process of making a scientific presentation from preparation to delivery. It offers numerous examples highlighting what to follow and what to avoid. This revised edition covers the effective use of PowerPointT and other computer-based presentation programs. It also includes a handy checklist, new illustrations, and tips on handling an audience in a foreign country.

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The extensively revised edition of the best-selling Focus Groups as Qualitative Research continues to provide an excellent guide for researchers across the disciplines.

Reflecting the many changes that have occurred in the study of focus groups in recent years, the book begins with an updated introduction offering a discussion of current social science approaches to focus groups. Expanded coverage on the comparison of focus groups to individual interviews follows, and there is more material on the strengths and weaknesses of focus groups. The section on self-contained focus groups has also been expanded. Subsequent chapters have been revised to include examples from social scientists who have established their own practices and methodological research on focus groups. In conclusion, the author offers future directions and references that take into account the explosive growth of focus groups as a research tool for all social scientists.

Medical Uses of Statistics, Second Edition Reviews

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This work explains the purpose of statistical methods in medical studies and analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in "The New England Journal of Medicine". It clarifies fundamental concepts of statistical design and analysis, and facilitates the understanding of research results.

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Behavioral techniques used in animals to model human diseases and predict effects of novel drugs are as varied as the numbers of scientists who use them. Consequently, behavioral analysis is becoming an increasingly indispensable tool for the neuroscientist as information gained at the molecular and cellular level is put into practice in fully behaving animal subjects.

Uses Animal Behavior Models to Examine Effects of Therapeutic Treatments on Human Cognition

With contributions from more than 40 field specialists, Methods of Behavioral Analysis in Neuroscience reflects six years worth of updates to its first bestselling edition and elucidates new behavioral approaches that are quickly becoming field standards. This edition features new material on the relevance of transgenic mouse models for Alzheimer’s disease, behavioral methods for assessing the cognitive impairment associated with major psychotic disorders, the revival of the scopolamine reversal model for assessing the clinical relevance of AD drugs, and approaches to assessing cognitive impairment in aged mice.

Each chapter presents theoretical background, methodology, and data interpretation, and many chapters include real-world examples of experiments that incorporate the models. With step-by-step, easy-to-reproduce methodologies, this sharply focused work covers well-studied behavioral approaches that provide a better understanding of the effects of disease and allow for better predictability of the effects of therapeutic treatments on the human cognition. It takes the guesswork out of designing the methodology for many of the most widely used animal behavioral approaches developed for the study of brain disorders, drug abuse, toxicology, and cognitive drug development.

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Building an up-to-date understanding of the methodologies that can be used to shape public health policies, Epidemiology: Study Design and Data Analysis, Second Edition encompasses the study of epidemiology from the observation of associations between risk factors and disease to the use of practical, data-supported analyses. It presents study designs commonly used for a wide range of purposes, and covers the spectrum of statistical principles and analytical tools used in epidemiological research, such as techniques used in report writing, descriptive analyses, statistical models and synthesis of evidence.

New Material in This Edition Includes:

Systematic evaluation

Meta-analysis

Regression dilution

Case-cohort studies

Case-crossover studies

Pooled logistic regression

Companion Web site containing data sets for examples and exercises, SAS and Stata code for examples, a sample size calculator, and a SAS floating absolute risk macro

The second edition of a popular textbook, this book emphasizes quantitative and design aspects of epidemiological research. The author favors the use of basic mathematics and practical methods over complicated mathematical proofs, making this an ideal textbook that is comprehensive yet accessible to graduate students in epidemiology, statistics, public health studies, and/or medical research.

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Electronic publishing and electronic means of text and data presentation have changed enormously since the first edition was first published in 1997. This second edition applies traditional principles to today's, modern techniques. In addition to substantial changes on the poster presentations and visual aids chapters, the chapter on proposal writing discusses in more detail grant writing proposals. A new chapter has also been dedicated to international students studying in the United States.


Selected Contents:
-Searching and Reviewing Scientific Literature
-The Graduate Thesis
-Publishing in Scientific Journals
-Reviewing and Revising
-Titles and Abstracts
-Ethical and Legal Issues
-Scientific Presentations
-Communication without words
-The Oral Presentation
-Poster Presentations

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Dissertations and Theses From Start to Finish: Psychology and Related Fields, Second Edition by American Psychological Association

Dissertations and Theses From Start to Finish: Psychology and Related Fields, Second Edition aids student writers through all the practical, logistical, and emotional stages of writing dissertations and theses. It offers guidance to students through such important steps as

• Defining topics;
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Readers will find guiding questions, both mundane and sophisticated, which they may never have considered before, even after coursework in preparation for research writing.

Authors have thoroughly updated the text for this new edition to reflect new ethical standards for research, new style manuals, and new texts in statistics, as well as current thinking on behavioral science research. They have also updated the 30+ special elements, adding entirely new checklists, diagrams, and sample parts of research papers. Also new to this edition is up-to-date information on computerized literature searches, writing and statistical software, and use of computers for data and schedule management.

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Approaches and techniques of clinical epidemiology have become increasingly prominent in veterinary literature. This second edition of Veterinary Clinical Epidemiology: A Problem-Oriented Approach reflects the increasing recognition of the role of clinical epidemiology by focusing on the application of epidemiologic principles and techniques of problems regularly faced by veterinary practitioners.

Numerous examples from veterinary literature indicate how experience with patients can be used to explore issues of importance in the practice of veterinary medicine while controlling for bias, confounding, and chance. The first part of the book focuses on the application of epidemiology in medical decision-making, while the second part focuses on the epidemiology of disease in populations and outbreak investigation.

Included in this text are a glossary and an extensive bibliography, as well as myriad updates to reflect the expanding use of epidemiologic methodology in clinical research. Veterinary Clinical Epidemiology: A Problem-Oriented Approach serves as both a teaching resource for veterinary epidemiology and a reference on the application of epidemiologic methods in veterinary clinical research.

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Designed for easy use by both beginning and experienced protein crystallographers, the second edition of Practical Protein Crystallography is an essential handbook for any scientist interested in solving a protein structure. The book includes examples of actual experiments and data, electron density maps, and computer methods. This second edition has new material covering CCP4, SHELX, cryocrystallography, MAD and automated fitting.

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Students and researchers all write under pressure, and those pressures—most lamentably, the desire to impress your audience rather than to communicate with them—often lead to pretentious prose, academic posturing, and, not infrequently, writer’s block.  

Sociologist Howard S. Becker has written the classic book on how to conquer these pressures and simply write. First published nearly twenty years ago, Writing for Social Scientists has become a lifesaver for writers in all fields, from beginning students to published authors. Becker’s message is clear: in order to learn how to write, take a deep breath and then begin writing. Revise. Repeat.

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In this new edition, Becker takes account of major changes in the computer tools available to writers today, and also substantially expands his analysis of how academic institutions create problems for them. As competition in academia grows increasingly heated, Writing for Social Scientists will provide solace to a new generation of frazzled, would-be writers.

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The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers.

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Swine in the Laboratory: Surgery, Anesthesia, Imaging, and Experimental Techniques, Second Edition by CRC Press




To diminish the learning curve associated with using swine as models, Swine in the Laboratory: Surgery, Anesthesia, Imaging, and Experimental Techniques, Second Edition provides practical technical information for the use of swine in biomedical research. The book focuses on models produced by surgical and other invasive procedures, supplying the basic principles for performing experiments with an organ or system of interest.

New to the Second Edition

Updated sections on anesthesia and perioperative care, including practical information for more complex models

Expansion of anatomic and physiologic details

Additional detail in the endoscopy section

Chapters on toxicology and radiobiology

Chapters that include angiographic, echocardiographic, CT, MRI, and PET imaging techniques with a corresponding DVD of the images

More tables of normal values on the most commonly used minipigs and domestic breeds

Beneficial for investigators, veterinarians, and technicians using swine for experimental and agricultural procedures, Swine in the Laboratory is certain to foster the appropriate, humane use of swine in biomedical research.

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Since its establishment by USDA regulation in the mid-1980s, the Institutional Animal Care and Use Committee (IACUC) has evolved as the premier instrument of animal welfare oversight within research institutions in the United States.

By addressing questions and problems that often confront institutions, The IACUC Handbook, Second Edition provides accurate, succinct answers. It features comprehensive updates for all pertinent federal laws, regulations, and policies. It also contains an expanded survey of IACUC practices from institutions around the nation.

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Noted for its comprehensive coverage, this greatly expanded new edition now covers the use of univariate and multivariate effect sizes. Many measures and estimators are reviewed along with their application, interpretation, and limitations. Noted for its practical approach, the book features numerous examples using real data for a variety of variables and designs, to help readers apply the material to their own data. Tips on the use of SPSS, SAS, R, and S-Plus are provided. The book's broad disciplinary appeal results from its inclusion of a variety of examples from psychology, medicine, education, and other social sciences. Special attention is paid to confidence intervals, the statistical assumptions of the methods, and robust estimators of effect sizes. The extensive reference section is appreciated by all.

With more than 40% new material, highlights of the new editon include:

• three new multivariate chapters covering effect sizes for analysis of covariance, multiple regression/correlation, and multivariate analysis of variance
• more learning tools in each chapter including introductions, summaries, "Tips and Pitfalls" and more conceptual and computational questions
• more coverage of univariate effect sizes, confidence intervals, and effect sizes for repeated measures to reflect their increased use in research
• more software references for calculating effect sizes and their confidence intervals including SPSS, SAS, R, and S-Plus
• the data used in the book are now provided on the web along with new data and suggested calculations with IBM SPSS syntax for computational practice.

Effect Sizes for Research covers standardized and unstandardized differences between means, correlational measures, strength of association, and parametric and nonparametric measures for between- and within-groups data.

Intended as a resource for professionals, researchers, and advanced students in a variety of fields, this book is also an excellent supplement for advanced statistics courses in psychology, education, the social sciences, business, and medicine. A prerequisite of introductory statistics through factorial analysis of variance and chi-square is recommended.

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This is a slim, benchtop reference collection of tips and warnings on the safe handling of chemicals and biologicals, listed alphabetically by compound. Extracted from a wide range of Cold Spring Harbor Laboratory Press manuals, this valuable information is presented in a handy format designed for easy use. The volume also includes helpful charts and tables.